Georgia O'Keeffe

Known for: large-scale flower and New Mexico landscape paintings

Georgia O'Keeffe developed a large-scale, close-up manner of painting flowers, bones, and the New Mexico landscape that had no real predecessor in American art and has had no real successor. She moved permanently to New Mexico after Alfred Stieglitz's death in 1946 and spent her final four decades painting the landscape she had documented for twenty years before. She is widely considered the most significant American woman painter of the twentieth century.